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You've probably seen the commercials touting Cialis as a way for men to overcome erectile dysfunction and carry on with their love lives, but you may wonder if that is the sole purpose of the drug and if that is the only reason it was formulated. Cialis, whose generic drug name is tadalafil, was discovered as a way to treat erectile dysfunction, or ED as it is also known, but it also is used to treat benign prostatic hyperplasia (BPH) and tadalafil has also been approved to treat pulmonary arterial hypertension.
Other Conditions Treated
BPH is a condition in which the prostate becomes enlarged and it can obstruct the flow of urine. Cialis can help treat the signs and symptoms of BPH, which include the urgency to urine, a weak urine flow, difficulty in urine starting to flow and frequent urination at night. The Federal Drug Administration (FDA) has also approved Cialis to treat BPH and ED when they co-exist.
Tadalafil has also been approved to treat a heart condition called pulmonary arterial hypertension, but it isn't treated under the brand name Cialis. The name for the medication to treat this condition is branded under Adcirca. Eli Lilly, who is the manufacturer of Cialis, sold the rights to sell tadalafil to treat the heart condition to Adcirca's maker United Therapeutics in late 2008 for $150 million.
History of Cialis
Under the brand name Cialis, the drug came into being in 1998. However, tadalafil actually was discovered in 1991 in a joint venture between GlaxoSmithKline and a biotech company called ICOS. It was later developed again and marketed worldwide in a venture with ICOS and Eli Lily called Lilly ICOS, LLC. It's development can be attributed to the success of the drug Viagra, which came onto the market in 1998 to treat ED. It made over $1 billion in sales in the US.
Even though Cialis was developed in 1998, the same year that Viagra made its ground breaking debut, it wasn't approved by the FDA until 2003. Because of its success and the ability for the effects of the drug to last approximately 36 hours, Cialis has become known as "The Weekend Pill".
In 2007, the Eli Lilly Co. bought ICOS for $2.3 billion dollars and is now the sole owner of Cialis. Sales of Cialis remain strong, topping $461.8 million in the first quarter of 2012, which was an increase of 6%. The drug was advertised during the 2004 Super Bowl, being the first medication of its kind to mention its side effects, but the ad was famously overshadowed by Janet Jackson's "wardrobe malfunction." Cialis uses some of its profits to sponsor several golf events, including the America's Cup and the PGA Tour.
Cialis General Information
The drug is prescribed in doses of 2.5 mg, 5mg, 10 and 20mg tablets. Only the 2.5 mg and 5mg tablets are recommended for daily use and of those two, only the 5mg is approved to treat ED and BPH. Besides the 5 mg, the 10 mg and 20mg tablets are the dosage that will last for 36 hours.
Cialis should not be taken with nitrate medications, such as nitroglycerine or other medication to treat chest pains or heart problems. If Cialis is taken with those medications, it could cause a serious and sudden decrease in blood pressure. Other drugs that can interact with Cialis include alpha-blockers, which are often prescribed to help with ED and for high blood pressure.
It also should be taken with certain antibiotics, including erythromycin, clarithromycin and telithromycin. Cialis can be affected by HIV drugs protease inhibitors, as well as some forms of oral antifungal drugs. Your doctor may have to adjust your dosage or run special tests if you take Cialis and have angina, heart disease, liver or kidney disease, among with several other diseases like leukemia or stomach ulcers.
Some of the serious side effects of Cialis include:
There are less serious side effects as well and they include:
What should I do if my daily dose of Cialis is missed?
You can take your dose whenever you remember it, but do not take Cialis more than one time per day.
Can I split my Cialis pills?
No, you shouldn't split the pills because you may end up getting the wrong dose of the drug and it could be ineffective to treat your erectile dysfunction or your benign prostatic hyperplasia (BPH). Cialis comes in fixed doses and your doctor will prescribe the correct dose for you.
Can elderly men take Cialis?
As long as they are in good health and do not have any conditions that may be affected by Cialis, any man can take the drug for the treatment of erectile dysfunction (ED) or BPH.
If a man is diabetic, can he take Cialis?
Men with type I or type II diabetes can take this drug and it has been proven effective for them to take to treat ED and BPH. Even though results may vary, in conducted studies, Cialis was successful in producing an erection allowing for sexual intercourse.
What is the difference between Cialis and other drugs to treat ED?
Some of the other drugs that treat ED do not last as long as Cialis can. There are doses of Cialis that are effective for up to 36 hours. These doses are usually 5 mg, 10mg or 20mg tablets.
Can women take Cialis?
There have been no tests or studies done on women in reference to taking this drug. Women should not take Cialis.
As with any drug regimen, you should never take it without first consulting your physician to see if you are healthy enough to take Cialis. Your doctor can check for drug interactions before you take it as well.
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